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Shrikrishna Tupare*,1, Pravin Chavan2, R. P. Pawar3
1Department of Chemistry, K. E. S. Anandibai Pradhan Science College, Nagothane, Raigad- 402106, Maharashtra, India.
2Department of Chemistry, Doshi Vakil College, Goregaon-Raigad-402103, Maharashtra, India.https://doi.org/10.33786/JCPR.2019.v09i04.027
Several substituted pyridazone derivative of Acetophenone are condensed with aromatic aldehydes, and resulting Chalcones are used for the synthesis of diarylpyrimidines. Organic compounds containing pyrimidines, thiopyrimidines as a core unit are known to exhibit various biological activities and pharmaceutical activities. So, all newly synthesized compounds were screened for their antibacterial activity. Most of the compounds showed significant antibacterial activities.
Pyrimidines, Guanidine, Antibacterial, Reflux.
CONFLICT OF INTEREST
The authors declare that they have no conflict of interest.
Received: 10 July 2019
Accepted: 27 August 2019