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Synthesis, Characterization and Antimicrobial Activity Analysis of Some New Schiff Bases.


Amol J. Shirsat1, Sunil S. Bhagat1, Balaji D. Rupnar1, Ajit K. Dhas2, Prashant Dixit3,Gopal K. Kakade*,4

1Department of Chemistry, R. B. Attal Arts, Science & Commerce College, Georai, Maharashtra,
India.


2Department of Chemistry, Deogiri College, Aurangabad, Maharashtra, India.


3Department of Microbiology, Dr. Babasaheb Ambedkar Marathwada University Sub-Center,
Osmanabad, Maharashtra, India.


4Department of Chemistry, Arts, Commerce & Science College, Kille-Dharur, Maharashtra,
India.

https://doi.org/10.33786/JCPR.2019.v10i01.003


First Online:2019-10-15

Cite As : Amol J. Shirsat, Sunil S. Bhagat, Balaji D. Rupnar, Ajit K. Dhas, Prashant Dixit, Gopal K. Kakade. 10, 1. https://doi.org/10.33786/JCPR.2019.v10i01.003

Corresponding Email id : shirsatamol@rediffmail.com

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Abstract

Schiff bases are generally one of the most commonly used organic moieties. They shows wide variety of applications in diverse fields including biological, analytical and inorganic chemistry they used as catalysts, pigments and dyes, intermediates in organic synthesis. Herein we report novel fluorine containing Schiff bases from 3-(5-bromothiophen-2-yl)-1-(4-fluorophenyl)-1Hpyrazole- 4-carbaldehyde and fluoroaniline. All synthesized Schiff bases were well characterized by spectral analysis and were screened for antimicrobial activity and successfully reported to show moderate activity.


KEY WORDS

Schiff bases, Pyrazole aldehyde, fluoroaniline, antimicrobial, Gram+ve and Gram–ve
microorganisms.


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Notes

ACKNOWLEDGEMENT 

 

CONFLICT OF INTEREST

The authors declare that they have no conflict of interest.


Copyright information

© Journal of Current Pharma Research


About this article

Received: 02 August 2019

Accepted: 11 October 2019


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