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Amol J. Shirsat1, Sunil S. Bhagat1, Balaji D. Rupnar1, Ajit K. Dhas2, Prashant Dixit3,Gopal K. Kakade*,4
1Department of Chemistry, R. B. Attal Arts, Science & Commerce College, Georai, Maharashtra,
2Department of Chemistry, Deogiri College, Aurangabad, Maharashtra, India.
3Department of Microbiology, Dr. Babasaheb Ambedkar Marathwada University Sub-Center,
Osmanabad, Maharashtra, India.
4Department of Chemistry, Arts, Commerce & Science College, Kille-Dharur, Maharashtra,
Schiff bases are generally one of the most commonly used organic moieties. They shows wide variety of applications in diverse fields including biological, analytical and inorganic chemistry they used as catalysts, pigments and dyes, intermediates in organic synthesis. Herein we report novel fluorine containing Schiff bases from 3-(5-bromothiophen-2-yl)-1-(4-fluorophenyl)-1Hpyrazole- 4-carbaldehyde and fluoroaniline. All synthesized Schiff bases were well characterized by spectral analysis and were screened for antimicrobial activity and successfully reported to show moderate activity.
Schiff bases, Pyrazole aldehyde, fluoroaniline, antimicrobial, Gram+ve and Gram–ve
CONFLICT OF INTEREST
The authors declare that they have no conflict of interest.
Received: 02 August 2019
Accepted: 11 October 2019