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Designing and Assessing of Atomoxetine Matrix Tablets Using Datura stramonium LeaveMucilage for the Treatment of Attention-Deficit Hyperactivity Disorder.


Hindustan Abdul Ahad*,1, Haranath Chintaginjala1, Manjoor Ahamad2, Gamaa BirirMohamed Musa1, Omer Ibrahim Abdulla Omer1, Birir Abdulla Birir Musa1, Osman AliOsman Ali1

1Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and
Research (RIPER), Autonomous, Ananthapuramu- 515721, Andhra Pradesh, India.


2Department of Pharmaceutical Chemistry, Raghavendra Institute of Pharmaceutical Education
and Research (RIPER), Autonomous- 515721, Andhra Pradesh, India.

https://doi.org/10.33786/JCPR.2020.v10i02.001


First Online:2020-01-11

Cite As : Hindustan Abdul Ahad, Haranath Chintaginjala, Manjoor Ahamad, Gamaa BirirMohamed Musa, Omer Ibrahim Abdulla Omer, Birir Abdulla Birir Musa, Osman AliOsman Ali. https://doi.org/10.33786/JCPR.2020.v10i02.001

Corresponding Email id : abdulhindustan@gmail.com

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Abstract

The authors aimed to extend discharge of Atomoxetine (ATX) tablets with a combination of herbal and synthetic polymers. ATX matrix tablets made with the blend of Datura stramonium leaves mucilage (DSLM) and Hydroxy Propyl Methyl Cellulose. The blend was assessed for flow possessions and the designed tablets were categorized for official and non official tests including ATX discharge. The ATX matrix tablets possess good ATX content with possible pre and post formulation parameters. The study concludes that there were no any chemical interactions between ATX with polymers used and DSLM can be a good polymer in grouping with other polymers for prolonged drug discharge.


KEY WORDS

Atomoxetine, Datura stramonium, mucilage, matrix.


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Notes

ACKNOWLEDGEMENT

 

CONFLICT OF INTEREST

The authors declare that they have no conflict of interest.


Copyright information

© Journal of Current Pharma Research


About this article

Received: 28 October 2019

Accepted: 01 January 2020


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