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Hindustan Abdul Ahad*,1, Haranath Chintaginjala1, Manjoor Ahamad2, Gamaa BirirMohamed Musa1, Omer Ibrahim Abdulla Omer1, Birir Abdulla Birir Musa1, Osman AliOsman Ali1
1Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and
Research (RIPER), Autonomous, Ananthapuramu- 515721, Andhra Pradesh, India.
2Department of Pharmaceutical Chemistry, Raghavendra Institute of Pharmaceutical Education
and Research (RIPER), Autonomous- 515721, Andhra Pradesh, India.
The authors aimed to extend discharge of Atomoxetine (ATX) tablets with a combination of herbal and synthetic polymers. ATX matrix tablets made with the blend of Datura stramonium leaves mucilage (DSLM) and Hydroxy Propyl Methyl Cellulose. The blend was assessed for flow possessions and the designed tablets were categorized for official and non official tests including ATX discharge. The ATX matrix tablets possess good ATX content with possible pre and post formulation parameters. The study concludes that there were no any chemical interactions between ATX with polymers used and DSLM can be a good polymer in grouping with other polymers for prolonged drug discharge.
Atomoxetine, Datura stramonium, mucilage, matrix.
CONFLICT OF INTEREST
The authors declare that they have no conflict of interest.
Received: 28 October 2019
Accepted: 01 January 2020